2022
2018
2018
2026
Anglas U, Tamez González AA, Promi MM, Zhu S, AlOkda A, Pacis A, Richard VR, Borchers CH, Van Raamsdonk JM. Elevated mitochondrial superoxide promotes longevity through a mitochondria-to-nucleus kinase signaling pathway. Redox Biol. 2026 Sep 8;97:104385. doi: 10.1016/j.redox.2026.104385. Epub ahead of print. PMID: 42721646.
Sung HK, Tang J, Lei Y, Nguyen K, Tam E, Wu J, Li RK, Richard V, Borchers CH, Antounians L, Burger D, Zani A, Sweeney G. ALY688 Protects Against Myocardial Ischemia-Reperfusion Injury via Direct Effects and Rab8a-Dependent Extracellular Vesicles. J Extracell Vesicles. 2026 Sep;15(9):e70357. doi: 10.1002/jev2.70357. PMID: 42667673; PMCID: PMC13525872.
Gaither C, Popp R, Maheshwari P, Lemus M, Laurin J, Filion M, Borchers CH. Overcoming Electrochemiluminescence Immunoassay (ECLIA) Limitations: Conformation-Independent Quantitation of a Therapeutic Antibody by LC-MS/MS. Anal Chem. 2026 Aug 18;98(32):23440-23449. doi: 10.1021/acs.analchem.5c07732. PMID: 42610927; PMCID: PMC13492046.
Hong LYQ, Batchu SN, Tran DT, Syeda MZ, Advani SL, Liu Y, Pacis A, Petrotchenko EV, Borchers CH, Yuen DA, Advani A. Sex-dependent control of renal tubular homeostasis and stress tolerance by KDM6A. bioRxiv [Preprint]. 2026 Jul 24:2026.07.22.740137. doi: 10.64898/2026.07.22.740137. PMID: 42539009; PMCID: PMC13419423.
Holm KY, Mohammed Y, Gunnarsdottir Thormar V, Eiríksson FF, Borchers CH, Sigurdsson S, Jonasson JG, Thorsteinsdottir M, Bodvarsdottir SK. Diagnostic plasma protein signatures in sporadic and BRCA1/2 breast cancer patients via targeted proteomics. Breast Cancer Res. 2026 Jul 18. doi: 10.1186/s13058-026-02348-y. Epub ahead of print. PMID: 42471715.
Blidjios C, Bhowmick P, Richard VR, Mohammed Y, Borchers CH. Enabling Variant Proteogenomic Assay Development Through a Peptide Target Selection Pipeline and Web Application. Proteomics. 2026 Sep;26(9):64-72. doi: 10.1002/pmic.70139. Epub 2026 May 17. PMID: 42143580; PMCID: PMC13519388.
Cho S, Sung HK, Nguyen K, Lei Y, Wannaiampikul S, Lee B, Tam E, Luo Y, Petrotchenko EV, Borchers CH, Prentice KJ, Summers SA, Burger D, Sweeney G. Lipidomic Analysis of Plasma Extracellular Vesicles from Adiponectin Deficient Mice or Metabolic Syndrome Patients Reveals Pro-Oxidative and Pro-Inflammatory Lipid Signatures Correlating with Metabolic Dysfunction. J Extracell Vesicles. 2026 Feb;15(2):e70229. doi: 10.1002/jev2.70229. PMID: 41656969; PMCID: PMC12884008.
Gu W, Wilkinson N, Fillebeen C, Blackburn DM, Sahinyan K, Bonneil E, Zhao T, Luo Z, Soleimani VD, Richard V, Borchers CH, Koulman A, Jenkins B, Michalke B, Zischka H, Sailer J, Venkataramani V, Iliopoulos O, Sweeney G, Pantopoulos K. IRP1 deficiency alters mitochondrial metabolism and protects against metabolic syndrome pathologies. JCI Insight. 2026 Jan 6;11(4):e183247. doi: 10.1172/jci.insight.183247. PMID: 41493805; PMCID: PMC12956002.
Camilleri E, van Vlijmen BJM, Bos MHA, Wuhrer M, Goodlett DR, Borchers CH, Cannegieter SC, van Rein N, Mohammed Y. Plasma proteomic profiles of patients during oral anti-coagulant treatment with vitamin K antagonists. Br J Haematol. 2026 Feb;208(2):763-768. doi: 10.1111/bjh.70278. Epub 2025 Dec 12. PMID: 41387349; PMCID: PMC12916191.
2025
Absar F, Novy B, Nagy E, Petrotchenko EV, Popov KI, Cross JB, Thapar R, Borchers CH. A Hit Prioritization Strategy for Compound Library Screening Using LiP-MS and Molecular Dynamics Simulations Applied to KRas G12D Inhibitors. Anal Chem. 2025 Sep 23;97(37):20228-20236. doi: 10.1021/acs.analchem.5c03103. Epub 2025 Sep 12. PMID: 40939179; PMCID: PMC12461684.
Mohammed Y, Bhowmick P, Borchers CH. MRMAssayDB: a comprehensive integrated resource for targeted proteomics assays. Expert Rev Proteomics. 2025 Oct;22(10):421-432. doi: 10.1080/14789450.2025.2557023. Epub 2025 Sep 18. PMID: 40900656.
Petrotchenko EV, Hahn A, Borchers CH. Determination of the Epitopes of Alpha-Glucosidase Anti-Drug Antibodies in Pompe Disease Patient Plasma Samples. Antibodies (Basel). 2025 Jul 28;14(3):64. doi: 10.3390/antib14030064. PMID: 40843676; PMCID: PMC12371896.
Petrotchenko EV, Novy B, Nagy E, Popov KI, Cross JB, Thapar R, Borchers CH. Characterization of the KRas G12D-inhibitor interactions by differential HDX-MS and molecular dynamics simulations. Comput Struct Biotechnol J. 2025 Aug 8;27:3618-3624. doi: 10.1016/j.csbj.2025.08.008. PMID: 40837237; PMCID: PMC12362407.
Gaither C, Popp R, Borchers CH, Beaudry F, Desmarchelier M. Plasma Proteomic Profiling of a Group of Anxious Dogs by LC-MS/MS: A Case-Control Study. Proteomics Clin Appl. 2025 Jul;19(4):e70014. doi: 10.1002/prca.70014. Epub 2025 Jul 4. PMID: 40614171; PMCID: PMC12278046.
Arnarson K, Y Holm K, Gunnarsdottir Thormar V, Eiríksson FF, Mohammed Y, Borchers CH, Bodvarsdottir SK, Thorsteinsdottir M. Optimization of bottom-up proteomic sample preparation by design of experiments for absolute quantification of 257 proteins in human plasma using UPLC-MRM-MS. Expert Rev Proteomics. 2025 May;22(5):209-216. doi: 10.1080/14789450.2025.2504994. Epub 2025 May 22. PMID: 40396504.
Mahdavi S, Rosychuk K, Jenkins DJA, Percy AJ, Borchers CH, El-Sohemy A. Multiomics Analysis of a Micronutrient-Rich Dietary Pattern and the Aging Genotype 9p21 on the Plasma Proteome of Young Adults. Nutrients. 2025 Apr 21;17(8):1398. doi: 10.3390/nu17081398. PMID: 40284261; PMCID: PMC12030164.
Mohammed Y, Richard VR, Reyes Madlangsakay MI, Lao Y, Spicer V, Popp R, Gaither C, Hennecken L, Kleinekofort W, Zahedi RP, Borchers CH. SysQuan: Repurposing SILAC Mice for the Cost-Effective Absolute Quantitation of the Human Proteome. Mol Cell Proteomics. 2025 Jun;24(6):100974. doi: 10.1016/j.mcpro.2025.100974. Epub 2025 Apr 18. PMID: 40254065; PMCID: PMC12143667.
Monette A, Aguilar-Mahecha A, Altinmakas E, Angelos MG, Assad N, Batist G, Bommareddy PK, Bonilla DL, Borchers CH, Church SE, Ciliberto G, Cogdill AP, Fattore L, Hacohen N, Haris M, Lacasse V, Lie WR, Mehta A, Ruella M, Sater S, Spatz A, Taouli B, Tarhoni I, Gonzalez-Kozlova E, Tirosh I, Wang X, Gnjatic S. The Society for Immunotherapy of Cancer Perspective on Liquid Biopsy- and Radiomics-Based Technologies for Immuno-oncology Biomarker Discovery and Application. Clin Cancer Res. 2025 Jun 13;31(12):2278-2293. doi: 10.1158/1078-0432.CCR-24-3791. PMID: 40197626.
Qasrawi DO, Pimenta AMC, Petrotchenko EV, Eintracht S, Borchers CH. Multiplexed Dilute-and-Shoot Liquid Chromatography-Multiple-Reaction Monitoring Mass Spectrometry Clinical Assay for Metanephrines and Catecholamines in Human Urine. Metabolites. 2025 Jan 8;15(1):30. doi: 10.3390/metabo15010030. PMID: 39852373; PMCID: PMC11767516.
Sobsey CA, Batist G, Borchers CH. Characterization of 53 Multiplexed Targeted Proteomics Assays for Verification Studies in Cancer Cell Lines. J Proteome Res. 2025 Feb 7;24(2):459-471. doi: 10.1021/acs.jproteome.4c00576. Epub 2025 Jan 13. PMID: 39804228; PMCID: PMC11812018.
Toumpanakis D, Vassilakopoulou V, Gu W, Mizi E, Chatzianastasiou A, Richard V, Borchers CH, Mohammed Y, Fillebeen C, Vassilakopoulos T, Pantopoulos K. Iron Regulatory Protein 2 Deficiency Is Protective Against Resistive Breathing-induced Pulmonary Inflammation. Am J Respir Cell Mol Biol. 2025 Jul;73(1):96-108. doi: 10.1165/rcmb.2024-0286OC. PMID: 39761600.
Mandal R, Zheng J, Zhang L, Oler E, LeVatte MA, Berjanskii M, Lipfert M, Han J, Borchers CH, Wishart DS. Comprehensive, Quantitative Analysis of SRM 1950: the NIST Human Plasma Reference Material. Anal Chem. 2025 Jan 14;97(1):667-675. doi: 10.1021/acs.analchem.4c05018. Epub 2025 Jan 5. PMID: 39757418; PMCID: PMC11740895.
Mitsa G, Florianova L, Lafleur J, Aguilar-Mahecha A, Zahedi RP, Del Rincon SV, Basik M, Borchers CH, Batist G. Clinical Proteomics Reveals Vulnerabilities in Noninvasive Breast Ductal Carcinoma and Drives Personalized Treatment Strategies. Cancer Res Commun. 2025 Jan 1;5(1):138-149. doi: 10.1158/2767-9764.CRC-24-0287. PMID: 39723668; PMCID: PMC11755405.
Gaither C, Popp R, Gajadhar AS, Borchers CH. Reproducible protein quantitation of 270 human proteins at increased depth using nanoparticle-based fractionation and multiple reaction monitoring mass spectrometry with stable isotope-labelled internal standards. Analyst. 2025 Jan 13;150(2):353-361. doi: 10.1039/d4an00967c. PMID: 39670628.
Monette A, Aguilar-Mahecha A, Altinmakas E, Angelos MG, Assad N, Batist G, Bommareddy PK, Bonilla DL, Borchers CH, Church SE, Ciliberto G, Cogdill AP, Fattore L, Hacohen N, Haris M, Lacasse V, Lie WR, Mehta A, Ruella M, Sater HA, Spatz A, Taouli B, Tarhoni I, Gonzalez-Kozlova E, Tirosh I, Wang X, Gnjatic S. The Society for Immunotherapy of Cancer Perspective on Tissue-Based Technologies for Immuno-Oncology Biomarker Discovery and Application. Clin Cancer Res. 2025 Feb 3;31(3):439-456. doi: 10.1158/1078-0432.CCR-24-2469. PMID: 39625818.
Méant A, Moussa O, Lebeau B, Gonçalves C, Richard VR, Cai F, Prabhu SA, Langke M, Guettler EM, Su J, Gagnon N, Zahedi RP, Borchers CH, Miller WH Jr, Del Rincón SV, Witcher M. Combined Inhibition of MNK Signaling and BET Proteins Reveals TGM2 as a Novel Vulnerability in Melanoma. J Invest Dermatol. 2025 Apr;145(4):979-984.e5. doi: 10.1016/j.jid.2024.07.037. Epub 2024 Oct 1. PMID: 39357785.
2024
Balasubramaniam NK, Penberthy S, Fenyo D, Viessmann N, Russmann C, Borchers CH. Digitalomics - digital transformation leading to omics insights. Expert Rev Proteomics. 2024 Sep-Oct;21(9-10):337-344. doi: 10.1080/14789450.2024.2413107. Epub 2024 Oct 11. PMID: 39364775.
Preston SEJ, Dahabieh MS, Flores González RE, Gonçalves C, Richard VR, Leibovitch M, Dakin E, Papadopoulos T, Lopez Naranjo C, McCallum PA, Huang F, Gagnon N, Perrino S, Zahedi RP, Borchers CH, Jones RG, Brodt P, Miller WH Jr, Del Rincón SV. Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis. Sci Adv. 2024 Sep 13;10(37):eadi7673. doi: 10.1126/sciadv.adi7673. Epub 2024 Sep 13. PMID: 39270021; PMCID: PMC11397505.
Rahimian R, Perlman K, Fakhfouri G, Mpai R, Richard VR, Hercher C, Penney L, Davoli MA, Nagy C, Zahedi RP, Borchers CH, Giros B, Turecki G, Mechawar N. Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb. Brain Behav Immun. 2024 Nov;122:110-121. doi: 10.1016/j.bbi.2024.08.016. Epub 2024 Aug 14. PMID: 39128570.
Blackburn DM, Sahinyan K, Hernández-Corchado A, Lazure F, Richard V, Raco L, Perron G, Zahedi RP, Borchers CH, Lepper C, Kawabe H, Jahani-Asl A, Najafabadi HS, Soleimani VD. The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation. iScience. 2024 Jun 11;27(7):110241. doi: 10.1016/j.isci.2024.110241. PMID: 39015146; PMCID: PMC11250905.
Sobsey CA, Froehlich BC, Mitsa G, Ibrahim S, Popp R, Zahedi RP, de Bruin EC, Borchers CH, Batist G. mTORC1-Driven Protein Translation Correlates with Clinical Benefit of Capivasertib within a Genetically Preselected Cohort of PIK3CA-Altered Tumors. Cancer Res Commun. 2024 Aug 1;4(8):2058-2074. doi: 10.1158/2767-9764.CRC-24-0113. PMID: 38954770; PMCID: PMC11320025.
Carvalho Cabral P, Richard VR, Borchers CH, Olivier M, Cermakian N. Circadian Control of the Response of Macrophages to Plasmodium Spp.-Infected Red Blood Cells. Immunohorizons. 2024 Jun 1;8(6):442-456. doi: 10.4049/immunohorizons.2400021. PMID: 38916585; PMCID: PMC11220744.
Richard VR, Mitsa G, Eshghi A, Chaplygina D, Mohammed Y, Goodlett DR, Zahedi RP, Thevis M, Borchers CH. Establishing Personalized Blood Protein Reference Ranges Using Noninvasive Microsampling and Targeted Proteomics: Implications for Antidoping Strategies. J Proteome Res. 2024 May 3;23(5):1779-1787. doi: 10.1021/acs.jproteome.4c00020. Epub 2024 Apr 24. PMID: 38655860; PMCID: PMC11077581.
Anwar MA, Keshteli AH, Yang H, Wang W, Li X, Messier HM, Cullis PR, Borchers CH, Fraser R, Wishart DS. Blood-Based Multiomics-Guided Detection of a Precancerous Pancreatic Tumor. OMICS. 2024 Apr;28(4):182-192. doi: 10.1089/omi.2023.0278. Epub 2024 Apr 17. PMID: 38634790.
Qasrawi DO, Al-Ghabkari A, Khan RM, Petrotchenko EV, Montero-Odasso M, Borchers CH. A Simplified Proteomics LC-MRM-MS Assay for Determination of apoE Genotypes in Plasma Samples. J Proteome Res. 2024 Apr 5;23(4):1144-1149. doi: 10.1021/acs.jproteome.3c00557. Epub 2024 Feb 27. PMID: 38412507; PMCID: PMC11002930.
Sobsey CA, Mady N, Richard VR, LeBlanc A, Zakharov T, Borchers CH, Jagoe RT. Measurement of CYP1A2 and CYP3A4 activity by a simplified Geneva cocktail approach in a cohort of free-living individuals: a pilot study. Front Pharmacol. 2024 Feb 2;15:1232595. doi: 10.3389/fphar.2024.1232595. PMID: 38370474; PMCID: PMC10869543.
Luo VM, Shen C, Worme S, Bhagrath A, Simo-Cheyou E, Findlay S, Hébert S, Wai Lam Poon W, Aryanpour Z, Zhang T, Zahedi RP, Boulais J, Buchwald ZS, Borchers CH, Côté JF, Kleinman CL, Mandl JN, Orthwein A. The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2. Mol Cell Biol. 2024 Jan;44(1):1-16. doi: 10.1080/10985549.2023.2290434. Epub 2024 Jan 29. PMID: 38270191; PMCID: PMC10829841.
Michaud SA, Pětrošová H, Sinclair NJ, Kinnear AL, Jackson AM, McGuire JC, Hardie DB, Bhowmick P, Ganguly M, Flenniken AM, Nutter LMJ, McKerlie C, Smith D, Mohammed Y, Schibli D, Sickmann A, Borchers CH. Multiple reaction monitoring assays for large-scale quantitation of proteins from 20 mouse organs and tissues. Commun Biol. 2024 Jan 2;7(1):6. doi: 10.1038/s42003-023-05687-0. PMID: 38168632; PMCID: PMC10762018.
Mohammed Y, Tran K, Carlsten C, Ryerson C, Wong A, Lee T, Cheng MP, Vinh DC, Lee TC, Winston BW, Sweet D, Boyd JH, Walley KR, Haljan G, McGeer A, Lamontagne F, Fowler R, Maslove D, Singer J, Patrick DM, Marshall JC, Murthy S, Jain F, Borchers CH, Goodlett DR, Levin A, Russell JA; ARBs CORONA I Consortium. Proteomic Evolution from Acute to Post-COVID-19 Conditions. J Proteome Res. 2024 Jan 5;23(1):52-70. doi: 10.1021/acs.jproteome.3c00324. Epub 2023 Dec 4. PMID: 38048423; PMCID: PMC10775146.
Sultana M, Camicioli R, Dixon RA, Whitehead S, Pieruccini-Faria F, Petrotchenko E, Speechley M, Borchers CH, Montero-Odasso M. A Metabolomics Analysis of a Novel Phenotype of Older Adults at Higher Risk of Dementia. J Alzheimers Dis. 2024;99(s2):S317-S325. doi: 10.3233/JAD-230683. PMID: 37781807.
2023
Zhang AMY, Xia YH, Lin JSH, Chu KH, Wang WCK, Ruiter TJJ, Yang JCC, Chen N, Chhuor J, Patil S, Cen HH, Rideout EJ, Richard VR, Schaeffer DF, Zahedi RP, Borchers CH, Johnson JD, Kopp JL. Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation. Cell Metab. 2023 Dec 5;35(12):2119-2135.e5. doi: 10.1016/j.cmet.2023.10.003. Epub 2023 Oct 31. PMID: 37913768.
Wang K, Khoramjoo M, Srinivasan K, Gordon PMK, Mandal R, Jackson D, Sligl W, Grant MB, Penninger JM, Borchers CH, Wishart DS, Prasad V, Oudit GY. Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID. Cell Rep Med. 2023 Nov 21;4(11):101254. doi: 10.1016/j.xcrm.2023.101254. Epub 2023 Oct 26. PMID: 37890487; PMCID: PMC10694626.
Castillo-Castrejon M, Sankofi BM, Murguia SJ, Udeme AA, Cen HH, Xia YH, Thomas NS, Berry WL, Jones KL, Richard VR, Zahedi RP, Borchers CH, Johnson JD, Wellberg EA. FGF1 supports glycolytic metabolism through the estrogen receptor in endocrine-resistant and obesity-associated breast cancer. Breast Cancer Res. 2023 Aug 22;25(1):99. doi: 10.1186/s13058-023-01699-0. PMID: 37608351; PMCID: PMC10463730.
Petrotchenko EV, Nascimento EM, Witt JM, Borchers CH. Determination of Protein Monoclonal-Antibody Epitopes by a Combination of Structural Proteomics Methods. J Proteome Res. 2023 Sep 1;22(9):3096-3102. doi: 10.1021/acs.jproteome.3c00159. Epub 2023 Aug 1. PMID: 37526474; PMCID: PMC10476242.
Qasrawi DO, Petrotchenko EV, Borchers CH. Amino acid analysis for peptide quantitation using reversed-phase liquid chromatography combined with multiple reaction monitoring mass spectrometry. Anal Bioanal Chem. 2023 Sep;415(22):5261-5267. doi: 10.1007/s00216-023-04840-2. Epub 2023 Jul 19. PMID: 37468754; PMCID: PMC10444640.
Mitsa G, Richard VR, Majedi Y, Lafleur J, Aguilar-Mahecha A, Basik M, Borchers CH. Evaluation of a 'plug and play' nanoflow liquid chromatography system for MS-based proteomic characterization of clinical FFPE specimens. Expert Rev Proteomics. 2023 Apr-Jun;20(4-6):87-92. doi: 10.1080/14789450.2023.2219844. Epub 2023 Jun 13. PMID: 37309581.
Shahid I, Han J, Hanook S, Borchers CH, El Enshasy HA, Mehnaz S. Genome mining of Pseudomonas spp. hints towards the production of under-pitched secondary metabolites. 3 Biotech. 2023 Jun;13(6):182. doi: 10.1007/s13205-023-03607-x. Epub 2023 May 12. PMID: 37193329; PMCID: PMC10182215.
Yerra VG, Batchu SN, Kaur H, Kabir MDG, Liu Y, Advani SL, Tran DT, Sadeghian S, Sedrak P, Billia F, Kuzmanov U, Gramolini AO, Qasrawi DO, Petrotchenko EV, Borchers CH, Connelly KA, Advani A. Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure. J Clin Invest. 2023 May 1;133(9):e161453. doi: 10.1172/JCI161453. PMID: 37115698; PMCID: PMC10145941.
Reboucas P, Fillebeen C, Botta A, Cleverdon R, Steele AP, Richard V, Zahedi RP, Borchers CH, Burelle Y, Hawke TJ, Pantopoulos K, Sweeney G. Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of β-Thalassemia. Int J Mol Sci. 2023 Feb 23;24(5):4402. doi: 10.3390/ijms24054402. PMID: 36901833; PMCID: PMC10002226.
Mohammed Y, Goodlett D, Borchers CH. Bioinformatics Tools and Knowledgebases to Assist Generating Targeted Assays for Plasma Proteomics. Methods Mol Biol. 2023;2628:557-577. doi: 10.1007/978-1-0716-2978-9_32. PMID: 36781806.
Mohammed Y, Goodlett D, Borchers CH. Absolute Quantitative Targeted Proteomics Assays for Plasma Proteins. Methods Mol Biol. 2023;2628:439-473. doi: 10.1007/978-1-0716-2978-9_27. PMID: 36781801.
Gaither C, Popp R, Richard VR, Zahedi RP, Borchers CH. Offline Peptide Fractionation and Parallel Reaction Monitoring MS for the Quantitation of Low-Abundance Plasma Proteins. Methods Mol Biol. 2023;2628:353-364. doi: 10.1007/978-1-0716-2978-9_23. PMID: 36781797.
Prabhu SA, Moussa O, Gonçalves C, LaPierre JH, Chou H, Huang F, Richard VR, Ferruzo PYM, Guettler EM, Soria-Bretones I, Kirby L, Gagnon N, Su J, Silvester J, Krisna SS, Rose AAN, Sheppard KE, Cescon DW, Mallette FA, Zahedi RP, Borchers CH, Del Rincon SV, Miller WH. Inhibition of the MNK1/2-eIF4E Axis Augments Palbociclib-Mediated Antitumor Activity in Melanoma and Breast Cancer. Mol Cancer Ther. 2023 Feb 1;22(2):192-204. doi: 10.1158/1535-7163.MCT-22-0092. PMID: 36722142.
Preston SEJ, Richard VR, Del Rincón SV, Borchers CH, Zahedi RP. Proteomic Assessment of the Murine Mammary Gland Extracellular Matrix. Methods Mol Biol. 2023;2614:261-271. doi: 10.1007/978-1-0716-2914-7_16. PMID: 36587130.
2022
Parra ALC, Freitas CDT, Souza PFN, von Aderkas P, Borchers CH, Beattie GA, Silva FDA, Thornburg RW. Ornamental tobacco floral nectar is a rich source of antimicrobial peptides. Plant Sci. 2022 Nov;324:111427. doi: 10.1016/j.plantsci.2022.111427. Epub 2022 Aug 23. PMID: 36007629.
Richard VR, Gaither C, Popp R, Chaplygina D, Brzhozovskiy A, Kononikhin A, Mohammed Y, Zahedi RP, Nikolaev EN, Borchers CH. Early Prediction of COVID-19 Patient Survival by Targeted Plasma Multi-Omics and Machine Learning. Mol Cell Proteomics. 2022 Oct;21(10):100277. doi: 10.1016/j.mcpro.2022.100277. Epub 2022 Aug 3. PMID: 35931319; PMCID: PMC9345792.
Preston SEJ, Bartish M, Richard VR, Aghigh A, Gonçalves C, Smith-Voudouris J, Huang F, Thébault P, Cleret-Buhot A, Lapointe R, Légaré F, Postovit LM, Zahedi RP, Borchers CH, Miller WH Jr, Del Rincón SV. Phosphorylation of eIF4E in the stroma drives the production and spatial organisation of collagen type I in the mammary gland. Matrix Biol. 2022 Aug;111:264-288. doi: 10.1016/j.matbio.2022.07.003. Epub 2022 Jul 14. PMID: 35842012.
Sobsey CA, Froehlich B, Batist G, Borchers CH. Immuno-MALDI-MS for Accurate Quantitation of Targeted Peptides from Volume-Restricted Samples. Methods Mol Biol. 2022;2515:203-225. doi: 10.1007/978-1-0716-2409-8_13. PMID: 35776354.
Mitsa G, Guo Q, Goncalves C, Preston SEJ, Lacasse V, Aguilar-Mahecha A, Benlimame N, Basik M, Spatz A, Batist G, Miller WH Jr, Del Rincon SV, Zahedi RP, Borchers CH. A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens. Int J Mol Sci. 2022 Apr 18;23(8):4443. doi: 10.3390/ijms23084443. PMID: 35457260; PMCID: PMC9031572.
Laselva O, Petrotchenko EV, Hamilton CM, Qureshi Z, Borchers CH, Young RN, Bear CE. A protocol for identifying the binding sites of small molecules on the cystic fibrosis transmembrane conductance regulator (CFTR) protein. STAR Protoc. 2022 Apr 7;3(2):101258. doi: 10.1016/j.xpro.2022.101258. PMID: 35434660; PMCID: PMC9006651.
Gaither C, Popp R, Zahedi RP, Borchers CH. Multiple Reaction Monitoring-Mass Spectrometry Enables Robust Quantitation of Plasma Proteins Regardless of Whole Blood Processing Delays That May Occur in the Clinic. Mol Cell Proteomics. 2022 May;21(5):100212. doi: 10.1016/j.mcpro.2022.100212. Epub 2022 Feb 17. PMID: 35182769; PMCID: PMC9062485.
Jennings MJ, Kagiava A, Vendredy L, Spaulding EL, Stavrou M, Hathazi D, Grüneboom A, De Winter V, Gess B, Schara U, Pogoryelova O, Lochmüller H, Borchers CH, Roos A, Burgess RW, Timmerman V, Kleopa KA, Horvath R. NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice. Brain. 2022 Nov 21;145(11):3999-4015. doi: 10.1093/brain/awac055. PMID: 35148379; PMCID: PMC9679171.
Brzhozovskiy A, Kononikhin A, Bugrova AE, Kovalev GI, Schmit PO, Kruppa G, Nikolaev EN, Borchers CH. The Parallel Reaction Monitoring-Parallel Accumulation-Serial Fragmentation (prm-PASEF) Approach for Multiplexed Absolute Quantitation of Proteins in Human Plasma. Anal Chem. 2022 Feb 1;94(4):2016-2022. doi: 10.1021/acs.analchem.1c03782. Epub 2022 Jan 18. PMID: 35040635.
Petrotchenko EV, Borchers CH. Protein Chemistry Combined with Mass Spectrometry for Protein Structure Determination. Chem Rev. 2022 Apr 27;122(8):7488-7499. doi: 10.1021/acs.chemrev.1c00302. Epub 2021 Dec 30. PMID: 34968047.
Mohammed Y, Touw CE, Nemeth B, van Adrichem RA, Borchers CH, Rosendaal FR, van Vlijmen BJ, Cannegieter SC. Targeted proteomics for evaluating risk of venous thrombosis following traumatic lower-leg injury or knee arthroscopy. J Thromb Haemost. 2022 Mar;20(3):684-699. doi: 10.1111/jth.15623. Epub 2022 Jan 6. PMID: 34919779; PMCID: PMC9303526.
2021
Gaspar VP, Ibrahim S, Zahedi RP, Borchers CH. Utility, promise, and limitations of liquid chromatography-mass spectrometry-based therapeutic drug monitoring in precision medicine. J Mass Spectrom. 2021 Nov;56(11):e4788. doi: 10.1002/jms.4788. Epub 2021 Nov 4. PMID: 34738286; PMCID: PMC8597589.
Froehlich BC, Popp R, Sobsey CA, Ibrahim S, LeBlanc A, Mohammed Y, Buchanan M, Aguilar-Mahecha A, Pötz O, Chen MX, Spatz A, Basik M, Batist G, Zahedi RP, Borchers CH. A multiplexed, automated immuno-matrix assisted laser desorption/ionization mass spectrometry assay for simultaneous and precise quantitation of PTEN and p110α in cell lines and tumor tissues. Analyst. 2021 Oct 25;146(21):6566-6575. doi: 10.1039/d1an00165e. PMID: 34585690.
Serpa JJ, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. Structure of prion β-oligomers as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations. Proteomics. 2021 Nov;21(21-22):e2000298. doi: 10.1002/pmic.202000298. Epub 2021 Sep 16. PMID: 34482645; PMCID: PMC9285417.
Ibrahim S, Lan C, Chabot C, Mitsa G, Buchanan M, Aguilar-Mahecha A, Elchebly M, Poetz O, Spatz A, Basik M, Batist G, Zahedi RP, Borchers CH. Precise Quantitation of PTEN by Immuno-MRM: A Tool To Resolve the Breast Cancer Biomarker Controversy. Anal Chem. 2021 Aug 10;93(31):10816-10824. doi: 10.1021/acs.analchem.1c00975. Epub 2021 Jul 29. PMID: 34324311.
Gaither C, Popp R, Borchers SP, Skarphedinsson K, Eiriksson FF, Thorsteinsdóttir M, Mohammed Y, Borchers CH. Performance Assessment of a 125 Human Plasma Peptide Mixture Stored at Room Temperature for Multiple Reaction Monitoring-Mass Spectrometry. J Proteome Res. 2021 Sep 3;20(9):4292-4302. doi: 10.1021/acs.jproteome.1c00249. Epub 2021 Jul 16. PMID: 34270269.
Laselva O, Qureshi Z, Zeng ZW, Petrotchenko EV, Ramjeesingh M, Hamilton CM, Huan LJ, Borchers CH, Pomès R, Young R, Bear CE. Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator. iScience. 2021 May 15;24(6):102542. doi: 10.1016/j.isci.2021.102542. PMID: 34142049; PMCID: PMC8184517.
Mohammed Y, Michaud SA, Pětrošová H, Yang J, Ganguly M, Schibli D, Flenniken AM, Nutter LMJ, Adissu HA, Lloyd KCK, McKerlie C, Borchers CH. Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma. NPJ Syst Biol Appl. 2021 May 28;7(1):25. doi: 10.1038/s41540-021-00184-8. PMID: 34050187; PMCID: PMC8163790.
Tran JN, Günther OP, Sherwood KR, Fenninger F, Allan LL, Lan J, Sapir-Pichhadze R, Duquesnoy R, Claas F, Marsh SGE, McMaster WR, Keown PA; Genome Canada Transplant Consortium. High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation. Commun Biol. 2021 May 14;4(1):583. doi: 10.1038/s42003-021-01989-3. PMID: 33990681; PMCID: PMC8121953.
Percy AJ, Borchers CH. Detailed Method for Performing the ExSTA Approach in Quantitative Bottom-Up Plasma Proteomics. Methods Mol Biol. 2021;2228:353-384. doi: 10.1007/978-1-0716-1024-4_25. PMID: 33950503.
Li FKK, Gale RT, Petrotchenko EV, Borchers CH, Brown ED, Strynadka NCJ. Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. J Struct Biol. 2021 Jun;213(2):107733. doi: 10.1016/j.jsb.2021.107733. Epub 2021 Apr 2. PMID: 33819634.
Bhowmick P, Roome S, Borchers CH, Goodlett DR, Mohammed Y. An Update on MRMAssayDB: A Comprehensive Resource for Targeted Proteomics Assays in the Community. J Proteome Res. 2021 Apr 2;20(4):2105-2115. doi: 10.1021/acs.jproteome.0c00961. Epub 2021 Mar 8. PMID: 33683131; PMCID: PMC8041396.
Shahid I, Han J, Hardie D, Baig DN, Malik KA, Borchers CH, Mehnaz S. Profiling of antimicrobial metabolites of plant growth promoting Pseudomonas spp. isolated from different plant hosts. 3 Biotech. 2021 Feb;11(2):48. doi: 10.1007/s13205-020-02585-8. Epub 2021 Jan 11. PMID: 33489669; PMCID: PMC7801537.
Mohammed Y, Bhowmick P, Michaud SA, Sickmann A, Borchers CH. Mouse Quantitative Proteomics Knowledgebase: reference protein concentration ranges in 20 mouse tissues using 5000 quantitative proteomics assays. Bioinformatics. 2021 Jul 27;37(13):1900-1908. doi: 10.1093/bioinformatics/btab018. PMID: 33483739.
Michaud SA, Pětrošová H, Jackson AM, McGuire JC, Sinclair NJ, Ganguly M, Flenniken AM, Nutter LMJ, McKerlie C, Schibli D, Smith D, Borchers CH. Process and Workflow for Preparation of Disparate Mouse Tissues for Proteomic Analysis. J Proteome Res. 2021 Jan 1;20(1):305-316. doi: 10.1021/acs.jproteome.0c00399. Epub 2020 Nov 5. PMID: 33151080.
2020
Gaspar VP, Ibrahim S, Sobsey CA, Richard VR, Spatz A, Zahedi RP, Borchers CH. Direct and Precise Measurement of Bevacizumab Levels in Human Plasma Based on Controlled Methionine Oxidation and Multiple Reaction Monitoring. ACS Pharmacol Transl Sci. 2020 Nov 13;3(6):1304-1309. doi: 10.1021/acsptsci.0c00134. PMID: 33344903; PMCID: PMC7737317.
De Giorgi M, Jarrett KE, Burton JC, Doerfler AM, Hurley A, Li A, Hsu RH, Furgurson M, Patel KR, Han J, Borchers CH, Lagor WR. Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase. J Lipid Res. 2020 Dec;61(12):1675-1686. doi: 10.1194/jlr.RA120001006. Epub 2020 Oct 27. PMID: 33109681; PMCID: PMC7707164.
Leitner A, Bonvin AMJJ, Borchers CH, Chalkley RJ, Chamot-Rooke J, Combe CW, Cox J, Dong MQ, Fischer L, Götze M, Gozzo FC, Heck AJR, Hoopmann MR, Huang L, Ishihama Y, Jones AR, Kalisman N, Kohlbacher O, Mechtler K, Moritz RL, Netz E, Novak P, Petrotchenko E, Sali A, Scheltema RA, Schmidt C, Schriemer D, Sinz A, Sobott F, Stengel F, Thalassinos K, Urlaub H, Viner R, Vizcaíno JA, Wilkins MR, Rappsilber J. Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. Structure. 2020 Nov 3;28(11):1259-1268. doi: 10.1016/j.str.2020.09.011. Epub 2020 Oct 15. PMID: 33065067.
Eshghi A, Pistawka AJ, Liu J, Chen M, Sinclair NJT, Hardie DB, Elliott M, Chen L, Newman R, Mohammed Y, Borchers CH. Correction: Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation. Mol Cell Proteomics. 2020 Oct;19(10):1738. doi: 10.1074/mcp.AAC120.002331. Erratum for: Mol Cell Proteomics. 2020 Mar;19(3):540-553. doi: 10.1074/mcp.TIR119.001820. PMID: 33004661; PMCID: PMC8015001.
Chen D, Han J, Yang J, Schibli D, Zhang Z, Borchers CH. Supermolecule-assisted imaging of low-molecular-weight quaternary-ammonium compounds by MALDI-MS of their non-covalent complexes with cucurbit[7]uril. RSC Adv. 2020 Sep 15;10(56):34261-34265. doi: 10.1039/d0ra04604c. PMID: 35519074; PMCID: PMC9056735.
Kashirina DN, Brzhozovskiy AG, Pastushkova LK, Kononikhin AS, Borchers CH, Nikolaev EN, Larina IM. Semiquantitative Proteomic Research of Protein Plasma Profile of Volunteers in 21-Day Head-Down Bed Rest. Front Physiol. 2020 Jul 24;11:678. doi: 10.3389/fphys.2020.00678. PMID: 32848806; PMCID: PMC7396636.
Carvalho PC, Souza TACB, Gozzo FC, Borchers CH. Editorial. J Proteomics. 2020 Sep 30;228:103937. doi: 10.1016/j.jprot.2020.103937. Epub 2020 Aug 13. PMID: 32836145.
Richard VR, Zahedi RP, Eintracht S, Borchers CH. An LC-MRM assay for the quantification of metanephrines from dried blood spots for the diagnosis of pheochromocytomas and paragangliomas. Anal Chim Acta. 2020 Sep 1;1128:140-148. doi: 10.1016/j.aca.2020.06.020. Epub 2020 Jul 9. PMID: 32825898; PMCID: PMC7346842.
Nikolaev EN, Indeykina MI, Brzhozovskiy AG, Bugrova AE, Kononikhin AS, Starodubtseva NL, Petrotchenko EV, Kovalev GI, Borchers CH, Sukhikh GT. Mass-Spectrometric Detection of SARS-CoV-2 Virus in Scrapings of the Epithelium of the Nasopharynx of Infected Patients via Nucleocapsid N Protein. J Proteome Res. 2020 Nov 6;19(11):4393-4397. doi: 10.1021/acs.jproteome.0c00412. Epub 2020 Aug 19. PMID: 32786682.
Ibrahim S, Froehlich BC, Aguilar-Mahecha A, Aloyz R, Poetz O, Basik M, Batist G, Zahedi RP, Borchers CH. Using Two Peptide Isotopologues as Internal Standards for the Streamlined Quantification of Low-Abundance Proteins by Immuno-MRM and Immuno-MALDI. Anal Chem. 2020 Sep 15;92(18):12407-12414. doi: 10.1021/acs.analchem.0c02157. Epub 2020 Sep 1. PMID: 32786432.
Froehlich BC, Popp R, Sobsey CA, Ibrahim S, LeBlanc AM, Mohammed Y, Aguilar-Mahecha A, Poetz O, Chen MX, Spatz A, Basik M, Batist G, Zahedi RP, Borchers CH. Systematic Optimization of the iMALDI Workflow for the Robust and Straightforward Quantification of Signaling Proteins in Cancer Cells. Proteomics Clin Appl. 2020 Sep;14(5):e2000034. doi: 10.1002/prca.202000034. Epub 2020 Aug 9. PMID: 32643306; PMCID: PMC7539945.
Liu T, Wang RX, Han J, Qiu YL, Borchers CH, Ling V, Wang JS. Changes in plasma bile acid profiles after partial internal biliary diversion in PFIC2 patients. Ann Transl Med. 2020 Mar;8(5):185. doi: 10.21037/atm.2020.01.103. PMID: 32309332; PMCID: PMC7154393.
Gaither C, Popp R, Mohammed Y, Borchers CH. Determination of the concentration range for 267 proteins from 21 lots of commercial human plasma using highly multiplexed multiple reaction monitoring mass spectrometry. Analyst. 2020 May 18;145(10):3634-3644. doi: 10.1039/c9an01893j. PMID: 32255452.
Tilburg J, Michaud SA, Maracle CX, Versteeg HH, Borchers CH, van Vlijmen BJM, Mohammed Y. Plasma Protein Signatures of a Murine Venous Thrombosis Model and Slc44a2 Knockout Mice Using Quantitative-Targeted Proteomics. Thromb Haemost. 2020 Mar;120(3):423-436. doi: 10.1055/s-0040-1702229. Epub 2020 Mar 5. PMID: 32135565.
Makepeace KAT, Mohammed Y, Rudashevskaya EL, Petrotchenko EV, Vögtle FN, Meisinger C, Sickmann A, Borchers CH. Improving Identification of In-organello Protein-Protein Interactions Using an Affinity-enrichable, Isotopically Coded, and Mass Spectrometry-cleavable Chemical Crosslinker. Mol Cell Proteomics. 2020 Apr;19(4):624-639. doi: 10.1074/mcp.RA119.001839. Epub 2020 Feb 12. PMID: 32051233; PMCID: PMC7124466.
Bhardwaj M, Weigl K, Tikk K, Holland-Letz T, Schrotz-King P, Borchers CH, Brenner H. Multiplex quantitation of 270 plasma protein markers to identify a signature for early detection of colorectal cancer. Eur J Cancer. 2020 Mar;127:30-40. doi: 10.1016/j.ejca.2019.11.021. Epub 2020 Jan 21. PMID: 31972396.
Shin JJH, Liu P, Chan LJ, Ullah A, Pan J, Borchers CH, Burke JE, Stefan C, Smits GJ, Loewen CJR. pH Biosensing by PI4P Regulates Cargo Sorting at the TGN. Dev Cell. 2020 Feb 24;52(4):461-476.e4. doi: 10.1016/j.devcel.2019.12.010. Epub 2020 Jan 9. PMID: 31928972.
Eshghi A, Pistawka AJ, Liu J, Chen M, Sinclair NJT, Hardie DB, Elliott M, Chen L, Newman R, Mohammed Y, Borchers CH. Concentration Determination of >200 Proteins in Dried Blood Spots for Biomarker Discovery and Validation. Mol Cell Proteomics. 2020 Mar;19(3):540-553. doi: 10.1074/mcp.TIR119.001820. Epub 2020 Jan 2. Erratum in: Mol Cell Proteomics. 2020 Oct;19(10):1738. doi: 10.1074/mcp.AAC120.002331. PMID: 31896676; PMCID: PMC7050112.
Silva F, Guirgis A, von Aderkas P, Borchers CH, Thornburg R. LC-MS/MS based comparative proteomics of floral nectars reveal different mechanisms involved in floral defense of Nicotiana spp., Petunia hybrida and Datura stramonium. J Proteomics. 2020 Feb 20;213:103618. doi: 10.1016/j.jprot.2019.103618. Epub 2019 Dec 14. PMID: 31846763.
Mohammed Y, Kootte RS, Kopatz WF, Borchers CH, Büller HR, Versteeg HH, Nieuwdorp M, van Mens TE. The intestinal microbiome potentially affects thrombin generation in human subjects. J Thromb Haemost. 2020 Mar;18(3):642-650. doi: 10.1111/jth.14699. Epub 2019 Dec 27. PMID: 31808596; PMCID: PMC7065057.
Sobsey CA, Ibrahim S, Richard VR, Gaspar V, Mitsa G, Lacasse V, Zahedi RP, Batist G, Borchers CH. Targeted and Untargeted Proteomics Approaches in Biomarker Development. Proteomics. 2020 May;20(9):e1900029. doi: 10.1002/pmic.201900029. Epub 2020 Jan 30. PMID: 31729135.
Makepeace KAT, Brodie NI, Popov KI, Gudavicius G, Nelson CJ, Petrotchenko EV, Dokholyan NV, Borchers CH. Ligand-induced disorder-to-order transitions characterized by structural proteomics and molecular dynamics simulations. J Proteomics. 2020 Jan 16;211:103544. doi: 10.1016/j.jprot.2019.103544. Epub 2019 Nov 1. PMID: 31683063; PMCID: PMC6878985.
2019
Blank-Landeshammer B, Richard VR, Mitsa G, Marques M, LeBlanc A, Kollipara L, Feldmann I, Couetoux du Tertre M, Gambaro K, McNamara S, Spatz A, Zahedi RP, Sickmann A, Batist G, Borchers CH. Proteogenomics of Colorectal Cancer Liver Metastases: Complementing Precision Oncology with Phenotypic Data. Cancers (Basel). 2019 Dec 1;11(12):1907. doi: 10.3390/cancers11121907. PMID: 31805664; PMCID: PMC6966481.
Popov KI, Makepeace KAT, Petrotchenko EV, Dokholyan NV, Borchers CH. Insight into the Structure of the "Unstructured" Tau Protein. Structure. 2019 Nov 5;27(11):1710-1715.e4. doi: 10.1016/j.str.2019.09.003. Epub 2019 Oct 15. PMID: 31628033.
Martínez de Paz A, Khajavi L, Martin H, Claveria-Gimeno R, Tom Dieck S, Cheema MS, Sanchez-Mut JV, Moksa MM, Carles A, Brodie NI, Sheikh TI, Freeman ME, Petrotchenko EV, Borchers CH, Schuman EM, Zytnicki M, Velazquez-Campoy A, Abian O, Hirst M, Esteller M, Vincent JB, Malnou CE, Ausió J. MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2. Epigenetics Chromatin. 2019 Oct 10;12(1):63. doi: 10.1186/s13072-019-0298-1. PMID: 31601272; PMCID: PMC6786283.
Bhardwaj M, Gies A, Weigl K, Tikk K, Benner A, Schrotz-King P, Borchers CH, Brenner H. Evaluation and Validation of Plasma Proteins Using Two Different Protein Detection Methods for Early Detection of Colorectal Cancer. Cancers (Basel). 2019 Sep 25;11(10):1426. doi: 10.3390/cancers11101426. PMID: 31557860; PMCID: PMC6826652.
Pires ES, Hardoim CCP, Miranda KR, Secco DA, Lobo LA, de Carvalho DP, Han J, Borchers CH, Ferreira RBR, Salles JF, Domingues RMCP, Antunes LCM. The Gut Microbiome and Metabolome of Two Riparian Communities in the Amazon. Front Microbiol. 2019 Sep 4;10:2003. doi: 10.3389/fmicb.2019.02003. PMID: 31555238; PMCID: PMC6737013.
Sirois I, Aguilar-Mahecha A, Lafleur J, Fowler E, Vu V, Scriver M, Buchanan M, Chabot C, Ramanathan A, Balachandran B, Légaré S, Przybytkowski E, Lan C, Krzemien U, Cavallone L, Aleynikova O, Ferrario C, Guilbert MC, Benlimame N, Saad A, Alaoui-Jamali M, Saragovi HU, Josephy S, O'Flanagan C, Hursting SD, Richard VR, Zahedi RP, Borchers CH, Bareke E, Nabavi S, Tonellato P, Roy JA, Robidoux A, Marcus EA, Mihalcioiu C, Majewski J, Basik M. A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability. Mol Cancer Res. 2019 Dec;17(12):2492-2507. doi: 10.1158/1541-7786.MCR-19-0264. Epub 2019 Sep 19. PMID: 31537618.
Oyama Y, Bartman CM, Bonney S, Lee JS, Walker LA, Han J, Borchers CH, Buttrick PM, Aherne CM, Clendenen N, Colgan SP, Eckle T. Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Rep. 2019 Aug 6;28(6):1471-1484.e11. doi: 10.1016/j.celrep.2019.07.020. PMID: 31390562; PMCID: PMC6708043.
Parker CE, Warren Hines MRE, Mocanu V, Greer SF, Borchers CH. Mass Spectrometric Determination of Protein Ubiquitination. Methods Mol Biol. 2019;1934:191-221. doi: 10.1007/978-1-4939-9055-9_13. PMID: 31256381.
Mao F, Liu T, Hou X, Zhao H, He W, Li C, Jing Z, Sui J, Wang F, Liu X, Han J, Borchers CH, Wang JS, Li W. Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency. J Biol Chem. 2019 Aug 2;294(31):11853-11862. doi: 10.1074/jbc.RA118.007179. Epub 2019 Jun 14. PMID: 31201272; PMCID: PMC6682732.
Larina IM, Percy AJ, Yang J, Borchers CH, Nosovsky AM, Grigoriev AI, Nikolaev EN. Publisher Correction: Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts. Sci Rep. 2019 Jun 7;9(1):8570. doi: 10.1038/s41598-019-43121-w. Erratum for: Sci Rep. 2017 Aug 15;7(1):8142. doi: 10.1038/s41598-017-08432-w. PMID: 31171809; PMCID: PMC6554333.
Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. Conformational ensemble of native α-synuclein in solution as determined by short-distance crosslinking constraint-guided discrete molecular dynamics simulations. PLoS Comput Biol. 2019 Mar 27;15(3):e1006859. doi: 10.1371/journal.pcbi.1006859. PMID: 30917118; PMCID: PMC6453469.
Kashirina DN, Percy AJ, Pastushkova LK, Borchers CH, Kireev KS, Ivanisenko VA, Kononikhin AS, Nikolaev EN, Larina IM. The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins. BMC Med Genomics. 2019 Mar 13;12(Suppl 2):45. doi: 10.1186/s12920-019-0490-y. PMID: 30871558; PMCID: PMC6416832.
Teixeira F, Tse E, Castro H, Makepeace KAT, Meinen BA, Borchers CH, Poole LB, Bardwell JC, Tomás AM, Southworth DR, Jakob U. Chaperone activation and client binding of a 2-cysteine peroxiredoxin. Nat Commun. 2019 Feb 8;10(1):659. doi: 10.1038/s41467-019-08565-8. PMID: 30737390; PMCID: PMC6368585.
Anwar MA, Dai DL, Wilson-McManus J, Smith D, Francis GA, Borchers CH, McManus BM, Hill JS, Cohen Freue GV. Multiplexed LC-ESI-MRM-MS-based Assay for Identification of Coronary Artery Disease Biomarkers in Human Plasma. Proteomics Clin Appl. 2019 Jul;13(4):e1700111. doi: 10.1002/prca.201700111. Epub 2019 Jan 28. PMID: 30632678.
Shultis D, Mitra P, Huang X, Johnson J, Khattak NA, Gray F, Piper C, Czajka J, Hansen L, Wan B, Chinnaswamy K, Liu L, Wang M, Pan J, Stuckey J, Cierpicki T, Borchers CH, Wang S, Lei M, Zhang Y. Changing the Apoptosis Pathway through Evolutionary Protein Design. J Mol Biol. 2019 Feb 15;431(4):825-841. doi: 10.1016/j.jmb.2018.12.016. Epub 2019 Jan 6. PMID: 30625288; PMCID: PMC6876990.
Wang R, Sheps JA, Liu L, Han J, Chen PSK, Lamontagne J, Wilson PD, Welch I, Borchers CH, Ling V. Hydrophilic bile acids prevent liver damage caused by lack of biliary phospholipid in Mdr2-/- mice. J Lipid Res. 2019 Jan;60(1):85-97. doi: 10.1194/jlr.M088070. Epub 2018 Nov 11. PMID: 30416103; PMCID: PMC6314265.
2018
Han J, Higgins R, Lim MD, Atkinson K, Yang J, Lin K, Borchers CH. Isotope-labeling derivatization with 3-nitrophenylhydrazine for LC/multiple-reaction monitoring-mass-spectrometry-based quantitation of carnitines in dried blood spots. Anal Chim Acta. 2018 Dec 11;1037:177-187. doi: 10.1016/j.aca.2018.01.045. Epub 2018 Feb 5. PMID: 30292292.
Michaud SA, Sinclair NJ, Pětrošová H, Palmer AL, Pistawka AJ, Zhang S, Hardie DB, Mohammed Y, Eshghi A, Richard VR, Sickmann A, Borchers CH. Molecular phenotyping of laboratory mouse strains using 500 multiple reaction monitoring mass spectrometry plasma assays. Commun Biol. 2018 Jun 27;1:78. doi: 10.1038/s42003-018-0087-6. PMID: 30271959; PMCID: PMC6123701.
Zahedi RP, Parker CE, Borchers CH. Immuno-MALDI-TOF-MS in the Clinic. Clin Chem. 2018 Sep;64(9):1271-1272. doi: 10.1373/clinchem.2018.292136. Epub 2018 Jul 17. PMID: 30018057.
Penn AM, Bibok MB, Saly VK, Coutts SB, Lesperance ML, Balshaw RF, Votova K, Croteau NS, Trivedi A, Jackson AM, Hegedus J, Klourfeld E, Yu AYX, Zerna C, Modi J, Barber PA, Hoag G, Borchers CH; SpecTRA study group. Validation of a proteomic biomarker panel to diagnose minor-stroke and transient ischaemic attack: phase 2 of SpecTRA, a large scale translational study. Biomarkers. 2018 Dec;23(8):793-803. doi: 10.1080/1354750X.2018.1499130. Epub 2018 Aug 23. PMID: 30010432.
Wölter M, Okai CA, Smith DS, Ruß M, Rath W, Pecks U, Borchers CH, Glocker MO. Maternal Apolipoprotein B100 Serum Levels are Diminished in Pregnancies with Intrauterine Growth Restriction and Differentiate from Controls. Proteomics Clin Appl. 2018 Nov;12(6):e1800017. doi: 10.1002/prca.201800017. Epub 2018 Jul 23. PMID: 29956482.
Mahdavi S, Jenkins DJA, Borchers CH, El-Sohemy A. Genetic Variation in 9p21 and the Plasma Proteome. J Proteome Res. 2018 Aug 3;17(8):2649-2656. doi: 10.1021/acs.jproteome.8b00117. Epub 2018 Jul 19. PMID: 29905076.
Mnatsakanyan R, Shema G, Basik M, Batist G, Borchers CH, Sickmann A, Zahedi RP. Detecting post-translational modification signatures as potential biomarkers in clinical mass spectrometry. Expert Rev Proteomics. 2018 Jun;15(6):515-535. doi: 10.1080/14789450.2018.1483340. PMID: 29893147.
Bhowmick P, Mohammed Y, Borchers CH. MRMAssayDB: an integrated resource for validated targeted proteomics assays. Bioinformatics. 2018 Oct 15;34(20):3566-3571. doi: 10.1093/bioinformatics/bty385. PMID: 29762640; PMCID: PMC6184479.
Parker CE, Borchers CH. The Special Issue: Clinical Proteomics for Precision Medicine. Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201600144. PMID: 29521035.
Luehr TC, Koide EM, Wang X, Han J, Borchers CH, Helbing CC. Metabolomic insights into the effects of thyroid hormone on Rana [Lithobates] catesbeiana metamorphosis using whole-body Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI). Gen Comp Endocrinol. 2018 Sep 1;265:237-245. doi: 10.1016/j.ygcen.2018.02.012. Epub 2018 Feb 19. PMID: 29470956.
Liu T, Wang RX, Han J, Hao CZ, Qiu YL, Yan YY, Li LT, Wang NL, Gong JY, Lu Y, Zhang MH, Xie XB, Yang JC, You YJ, Li JQ, Knisely AS, Borchers CH, Ling V, Wang JS. Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations. Liver Int. 2018 Sep;38(9):1676-1685. doi: 10.1111/liv.13714. Epub 2018 Mar 12. PMID: 29412511.
Penn AM, Bibok MB, Saly VK, Coutts SB, Lesperance ML, Balshaw RF, Votova K, Croteau NS, Trivedi A, Jackson AM, Hegedus J, Klourfeld E, Yu AYX, Zerna C, Borchers CH; SpecTRA study group. Verification of a proteomic biomarker panel to diagnose minor stroke and transient ischaemic attack: phase 1 of SpecTRA, a large scale translational study. Biomarkers. 2018 May-Jun;23(4):392-405. doi: 10.1080/1354750X.2018.1434681. Epub 2018 Feb 12. PMID: 29385837.
Dilworth D, Gudavicius G, Xu X, Boyce AKJ, O'Sullivan C, Serpa JJ, Bilenky M, Petrochenko EV, Borchers CH, Hirst M, Swayne LA, Howard P, Nelson CJ. The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability. Nucleic Acids Res. 2018 Mar 16;46(5):2459-2478. doi: 10.1093/nar/gky008. PMID: 29361176; PMCID: PMC5861405.
Perzanowska A, Fatalska A, Wojtas G, Lewandowicz A, Michalak A, Krasowski G, Borchers CH, Dadlez M, Domanski D. An MRM-Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung Cancer Pleural Effusions. Proteomics Clin Appl. 2018 Mar;12(2). doi: 10.1002/prca.201700084. Epub 2018 Feb 7. PMID: 29352525.
Brodie NI, Huguet R, Zhang T, Viner R, Zabrouskov V, Pan J, Petrotchenko EV, Borchers CH. Top-Down Hydrogen-Deuterium Exchange Analysis of Protein Structures Using Ultraviolet Photodissociation. Anal Chem. 2018 Mar 6;90(5):3079-3082. doi: 10.1021/acs.analchem.7b03655. Epub 2018 Feb 1. PMID: 29336549.
Jardim A, Hardie DB, Boitz J, Borchers CH. Proteomic Profiling of Leishmania donovani Promastigote Subcellular Organelles. J Proteome Res. 2018 Mar 2;17(3):1194-1215. doi: 10.1021/acs.jproteome.7b00817. Epub 2018 Feb 5. PMID: 29332401.
Eshghi A, Borchers CH. Multiple Reaction Monitoring Using Double Isotopologue Peptide Standards for Protein Quantification. Methods Mol Biol. 2018;1788:193-214. doi: 10.1007/7651_2017_112. PMID: 29256172.
Han J, Higgins R, Lim MD, Lin K, Yang J, Borchers CH. Short-Term Stabilities of 21 Amino Acids in Dried Blood Spots. Clin Chem. 2018 Feb;64(2):400-402. doi: 10.1373/clinchem.2017.278457. Epub 2017 Nov 2. PMID: 29097508.
Mohammed Y, Pan J, Zhang S, Han J, Borchers CH. ExSTA: External Standard Addition Method for Accurate High-Throughput Quantitation in Targeted Proteomics Experiments. Proteomics Clin Appl. 2018 Mar;12(2):1600180. doi: 10.1002/prca.201600180. Epub 2017 Oct 25. PMID: 28895300; PMCID: PMC6084352.
2017
Mohammed Y, van Vlijmen BJ, Yang J, Percy AJ, Palmblad M, Borchers CH, Rosendaal FR. Multiplexed targeted proteomic assay to assess coagulation factor concentrations and thrombosis-associated cancer. Blood Adv. 2017 Jun 20;1(15):1080-1087. doi: 10.1182/bloodadvances.2017007955. PMID: 29296750; PMCID: PMC5728326.
Urao N, Mirza RE, Corbiere TF, Hollander Z, Borchers CH, Koh TJ. Thrombospondin-1 and disease progression in dysferlinopathy. Hum Mol Genet. 2017 Dec 15;26(24):4951-4960. doi: 10.1093/hmg/ddx378. PMID: 29206970.
Dilworth D, Upadhyay SK, Bonnafous P, Edoo AB, Bourbigot S, Pesek-Jardim F, Gudavicius G, Serpa JJ, Petrotchenko EV, Borchers CH, Nelson CJ, Mackereth CD. The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module. Nucleic Acids Res. 2017 Nov 16;45(20):11989-12004. doi: 10.1093/nar/gkx852. PMID: 29036638; PMCID: PMC5714180.
Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S. Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma. J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6. PMID: 28986437; PMCID: PMC5711491.
Li H, Popp R, Frohlich B, Chen MX, Borchers CH. Peptide and Protein Quantification Using Automated Immuno-MALDI (iMALDI). J Vis Exp. 2017 Aug 18;(126):55933. doi: 10.3791/55933. PMID: 28872133; PMCID: PMC5614345.
Popp R, Li H, LeBlanc A, Mohammed Y, Aguilar-Mahecha A, Chambers AG, Lan C, Poetz O, Basik M, Batist G, Borchers CH. Immuno-Matrix-Assisted Laser Desorption/Ionization Assays for Quantifying AKT1 and AKT2 in Breast and Colorectal Cancer Cell Lines and Tumors. Anal Chem. 2017 Oct 3;89(19):10592-10600. doi: 10.1021/acs.analchem.7b02934. Epub 2017 Sep 20. PMID: 28853539.
Guarna MM, Hoover SE, Huxter E, Higo H, Moon KM, Domanski D, Bixby MEF, Melathopoulos AP, Ibrahim A, Peirson M, Desai S, Micholson D, White R, Borchers CH, Currie RW, Pernal SF, Foster LJ. Peptide biomarkers used for the selective breeding of a complex polygenic trait in honey bees. Sci Rep. 2017 Aug 21;7(1):8381. doi: 10.1038/s41598-017-08464-2. PMID: 28827652; PMCID: PMC5566959.
Larina IM, Percy AJ, Yang J, Borchers CH, Nosovsky AM, Grigoriev AI, Nikolaev EN. Protein expression changes caused by spaceflight as measured for 18 Russian cosmonauts. Sci Rep. 2017 Aug 15;7(1):8142. doi: 10.1038/s41598-017-08432-w. Erratum in: Sci Rep. 2019 Jun 7;9(1):8570. doi: 10.1038/s41598-019-43121-w. PMID: 28811532; PMCID: PMC5557884.
Richard VR, Domanski D, Percy AJ, Borchers CH. An online 2D-reversed-phase - Reversed-phase chromatographic method for sensitive and robust plasma protein quantitation. J Proteomics. 2017 Sep 25;168:28-36. doi: 10.1016/j.jprot.2017.07.018. Epub 2017 Jul 28. PMID: 28757464.
Pedde RD, Li H, Borchers CH, Akbari M. Microfluidic-Mass Spectrometry Interfaces for Translational Proteomics. Trends Biotechnol. 2017 Oct;35(10):954-970. doi: 10.1016/j.tibtech.2017.06.006. Epub 2017 Jul 26. PMID: 28755975.
Peixoto RJM, Alves ES, Wang M, Ferreira RBR, Granato A, Han J, Gill H, Jacobson K, Lobo LA, Domingues RMCP, Borchers CH, Davies JE, Finlay BB, Antunes LCM. Repression of Salmonella Host Cell Invasion by Aromatic Small Molecules from the Human Fecal Metabolome. Appl Environ Microbiol. 2017 Sep 15;83(19):e01148-17. doi: 10.1128/AEM.01148-17. PMID: 28754707; PMCID: PMC5601338.
Brodie NI, Popov KI, Petrotchenko EV, Dokholyan NV, Borchers CH. Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations. Sci Adv. 2017 Jul 7;3(7):e1700479. doi: 10.1126/sciadv.1700479. PMID: 28695211; PMCID: PMC5501500.
LeBlanc A, Michaud SA, Percy AJ, Hardie DB, Yang J, Sinclair NJ, Proudfoot JI, Pistawka A, Smith DS, Borchers CH. Multiplexed MRM-Based Protein Quantitation Using Two Different Stable Isotope-Labeled Peptide Isotopologues for Calibration. J Proteome Res. 2017 Jul 7;16(7):2527-2536. doi: 10.1021/acs.jproteome.7b00094. Epub 2017 Jun 2. PMID: 28516774.
Reynolds LA, Redpath SA, Yurist-Doutsch S, Gill N, Brown EM, van der Heijden J, Brosschot TP, Han J, Marshall NC, Woodward SE, Valdez Y, Borchers CH, Perona-Wright G, Finlay BB. Enteric Helminths Promote Salmonella Coinfection by Altering the Intestinal Metabolome. J Infect Dis. 2017 Apr 15;215(8):1245-1254. doi: 10.1093/infdis/jix141. PMID: 28368463; PMCID: PMC5853568.
Streijger F, Skinnider MA, Rogalski JC, Balshaw R, Shannon CP, Prudova A, Belanger L, Ritchie L, Tsang A, Christie S, Parent S, Mac-Thiong JM, Bailey C, Urquhart J, Ailon T, Paquette S, Boyd M, Street J, Fisher CG, Dvorak MF, Borchers CH, Foster LJ, Kwon BK. A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord Injury. J Neurotrauma. 2017 Jun 15;34(12):2054-2068. doi: 10.1089/neu.2016.4879. Epub 2017 Apr 7. PMID: 28276985.
Li H, Popp R, Chen M, MacNamara EM, Juncker D, Borchers CH. Bead-Extractor Assisted Ready-to-Use Reagent System (BEARS) for Immunoprecipitation Coupled to MALDI-MS. Anal Chem. 2017 Apr 4;89(7):3834-3839. doi: 10.1021/acs.analchem.6b04169. Epub 2017 Mar 16. PMID: 28257572.
Borchers CH, Thibault P. Corrigendum to "Introduction to the HUPO 2015 Special Issue" [J. Proteomics (2016) 1-2]. J Proteomics. 2017 Jan 30;152:355-356. doi: 10.1016/j.jprot.2016.12.005. PMID: 28062015.
Qiu YL, Gong JY, Feng JY, Wang RX, Han J, Liu T, Lu Y, Li LT, Zhang MH, Sheps JA, Wang NL, Yan YY, Li JQ, Chen L, Borchers CH, Sipos B, Knisely AS, Ling V, Xing QH, Wang JS. Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis. Hepatology. 2017 May;65(5):1655-1669. doi: 10.1002/hep.29020. Epub 2017 Mar 23. Erratum in: Hepatology. 2017 Nov;66(5):1708-1709. doi: 10.1002/hep.29552. PMID: 28027573; PMCID: PMC5413810.
Wang X, Han J, Hardie DB, Yang J, Pan J, Borchers CH. Metabolomic profiling of prostate cancer by matrix assisted laser desorption/ionization-Fourier transform ion cyclotron resonance mass spectrometry imaging using Matrix Coating Assisted by an Electric Field (MCAEF). Biochim Biophys Acta Proteins Proteom. 2017 Jul;1865(7):755-767. doi: 10.1016/j.bbapap.2016.12.012. Epub 2016 Dec 23. PMID: 28017863.
Bautista-López NL, Ndao M, Camargo FV, Nara T, Annoura T, Hardie DB, Borchers CH, Jardim A. Characterization and Diagnostic Application of Trypanosoma cruzi Trypomastigote Excreted-Secreted Antigens Shed in Extracellular Vesicles Released from Infected Mammalian Cells. J Clin Microbiol. 2017 Mar;55(3):744-758. doi: 10.1128/JCM.01649-16. Epub 2016 Dec 14. PMID: 27974541; PMCID: PMC5328442.
Percy AJ, Hardie DB, Jardim A, Yang J, Elliott MH, Zhang S, Mohammed Y, Borchers CH. Multiplexed panel of precisely quantified salivary proteins for biomarker assessment. Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600230. Epub 2016 Oct 19. PMID: 27538354.
Baker TC, Han J, Borchers CH. Recent advancements in matrix-assisted laser desorption/ionization mass spectrometry imaging. Curr Opin Biotechnol. 2017 Feb;43:62-69. doi: 10.1016/j.copbio.2016.09.003. Epub 2016 Sep 28. PMID: 27690313.
Percy AJ, Michaud SA, Jardim A, Sinclair NJ, Zhang S, Mohammed Y, Palmer AL, Hardie DB, Yang J, LeBlanc AM, Borchers CH. Multiplexed MRM-based assays for the quantitation of proteins in mouse plasma and heart tissue. Proteomics. 2017 Apr;17(7). doi: 10.1002/pmic.201600097. Epub 2016 Nov 18. PMID: 27688154.
Mohammed Y, Bhowmick P, Smith DS, Domanski D, Jackson AM, Michaud SA, Malchow S, Percy AJ, Chambers AG, Palmer A, Zhang S, Sickmann A, Borchers CH. PeptideTracker: A knowledge base for collecting and storing information on protein concentrations in biological tissues. Proteomics. 2017 Apr;17(7). doi: 10.1002/pmic.201600210. Epub 2016 Dec 14. PMID: 27683069.
2016
Percy AJ, Yang J, Chambers AG, Mohammed Y, Miliotis T, Borchers CH. Protocol for Standardizing High-to-Moderate Abundance Protein Biomarker Assessments Through an MRM-with-Standard-Peptides Quantitative Approach. Adv Exp Med Biol. 2016;919:515-530. doi: 10.1007/978-3-319-41448-5_24. PMID: 27975233.
Brodie NI, Petrotchenko EV, Borchers CH. The novel isotopically coded short-range photo-reactive crosslinker 2,4,6-triazido-1,3,5-triazine (TATA) for studying protein structures. J Proteomics. 2016 Oct 21;149:69-76. doi: 10.1016/j.jprot.2016.02.024. Epub 2016 Feb 28. PMID: 26931439.
Han J, Yi Y, Lin K, Birks SJ, Gibson JJ, Borchers CH. Molecular profiling of naphthenic acids in technical mixtures and oil sands process-affected water using polar reversed-phase liquid chromatography-mass spectrometry. Electrophoresis. 2016 Dec;37(23-24):3089-3100. doi: 10.1002/elps.201600250. Epub 2016 Oct 20. PMID: 27667503.
Pan J, Zhang S, Borchers CH. Comparative higher-order structure analysis of antibody biosimilars using combined bottom-up and top-down hydrogen-deuterium exchange mass spectrometry. Biochim Biophys Acta. 2016 Dec;1864(12):1801-1808. doi: 10.1016/j.bbapap.2016.08.013. Epub 2016 Aug 25. PMID: 27569733.
Yang J, Finke JC, Yang J, Percy AJ, von Fritschen U, Borchers CH, Glocker MO. Early risk prognosis of free-flap transplant failure by quantitation of the macrophage colony-stimulating factor in patient plasma using 2-dimensional liquid-chromatography multiple reaction monitoring-mass spectrometry. Medicine (Baltimore). 2016 Sep;95(39):e4808. doi: 10.1097/MD.0000000000004808. PMID: 27684807; PMCID: PMC5265900.
Bround MJ, Wambolt R, Cen H, Asghari P, Albu RF, Han J, McAfee D, Pourrier M, Scott NE, Bohunek L, Kulpa JE, Chen SR, Fedida D, Brownsey RW, Borchers CH, Foster LJ, Mayor T, Moore ED, Allard MF, Johnson JD. Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase. J Biol Chem. 2016 Nov 4;291(45):23490-23505. doi: 10.1074/jbc.M116.756973. Epub 2016 Sep 12. PMID: 27621312; PMCID: PMC5095405.
Sobsey CA, Han J, Lin K, Swardfager W, Levitt A, Borchers CH. Development and evaluation of a liquid chromatography-mass spectrometry method for rapid, accurate quantitation of malondialdehyde in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 1;1029-1030:205-212. doi: 10.1016/j.jchromb.2016.07.013. Epub 2016 Jul 7. PMID: 27437618.
Han J, Lin K, Sequria C, Yang J, Borchers CH. Quantitation of low molecular weight sugars by chemical derivatization-liquid chromatography/multiple reaction monitoring/mass spectrometry. Electrophoresis. 2016 Jul;37(13):1851-60. doi: 10.1002/elps.201600150. Epub 2016 May 27. PMID: 27120558.
Ellard K, Serpa JJ, Petrotchenko EV, Borchers CH, Ausió J. Expression and purification of the full murine NPM2 and study of its interaction with protamines and histones. Biochem Biophys Rep. 2016 Apr 8;6:165-171. doi: 10.1016/j.bbrep.2016.04.002. PMID: 28955874; PMCID: PMC5600342.
Percy AJ, Yang J, Chambers AG, Borchers CH. Increased Depth and Breadth of Plasma Protein Quantitation via Two-Dimensional Liquid Chromatography/Multiple Reaction Monitoring-Mass Spectrometry with Labeled Peptide Standards. Methods Mol Biol. 2016;1410:1-21. doi: 10.1007/978-1-4939-3524-6_1. PMID: 26867735.
Pan J, Zhang S, Chou A, Borchers CH. Higher-order structural interrogation of antibodies using middle-down hydrogen/deuterium exchange mass spectrometry. Chem Sci. 2016 Feb 1;7(2):1480-1486. doi: 10.1039/c5sc03420e. Epub 2015 Nov 24. PMID: 29910905; PMCID: PMC5975933.
Groitl B, Horowitz S, Makepeace KAT, Petrotchenko EV, Borchers CH, Reichmann D, Bardwell JCA, Jakob U. Protein unfolding as a switch from self-recognition to high-affinity client binding. Nat Commun. 2016 Jan 20;7:10357. doi: 10.1038/ncomms10357. PMID: 26787517; PMCID: PMC4735815.
Wang X, Han J, Hardie DB, Yang J, Borchers CH. The use of matrix coating assisted by an electric field (MCAEF) to enhance mass spectrometric imaging of human prostate cancer biomarkers. J Mass Spectrom. 2016 Jan;51(1):86-95. doi: 10.1002/jms.3728. PMID: 26757076.
Pan J, Zhang S, Borchers CH. Protein species-specific characterization of conformational change induced by multisite phosphorylation. J Proteomics. 2016 Feb 16;134:138-143. doi: 10.1016/j.jprot.2015.12.002. Epub 2015 Dec 7. PMID: 26675311.
Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, Han J, Fan Y, Lynn FC, Trucco M, Borchers CH, Foster LJ, Nislow C, Kieffer TJ, Johnson JD. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation. Cell Metab. 2016 Jan 12;23(1):179-93. doi: 10.1016/j.cmet.2015.10.016. Epub 2015 Nov 25. PMID: 26626461.
2015
Percy AJ, Mohammed Y, Yang J, Borchers CH. A standardized kit for automated quantitative assessment of candidate protein biomarkers in human plasma. Bioanalysis. 2015 Dec;7(23):2991-3004. doi: 10.4155/bio.15.222. Epub 2015 Dec 2. PMID: 26626236.
Parker CE, Borchers CH. Editorial. Methods. 2015 Nov 1;89:1-3. doi: 10.1016/j.ymeth.2015.10.010. PMID: 26552894.
Penn AM, Lu L, Chambers AG, Balshaw RF, Morrison JL, Votova K, Wood E, Smith DS, Lesperance M, del Zoppo GJ, Borchers CH; SpecTRA Study Group. Exploring phlebotomy technique as a pre-analytical factor in proteomic analyses by mass spectrometry. Genome. 2015 Dec;58(12):569-76. doi: 10.1139/gen-2015-0036. Epub 2015 Jul 10. PMID: 26484650.
Hagel JM, Mandal R, Han B, Han J, Dinsmore DR, Borchers CH, Wishart DS, Facchini PJ. Metabolome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants. BMC Plant Biol. 2015 Sep 15;15:220. doi: 10.1186/s12870-015-0594-2. PMID: 26369413; PMCID: PMC4570626.
Chambers AG, Percy AJ, Yang J, Borchers CH. Multiple Reaction Monitoring Enables Precise Quantification of 97 Proteins in Dried Blood Spots. Mol Cell Proteomics. 2015 Nov;14(11):3094-104. doi: 10.1074/mcp.O115.049957. Epub 2015 Sep 4. PMID: 26342038; PMCID: PMC4638049.
Brown EM, Wlodarska M, Willing BP, Vonaesch P, Han J, Reynolds LA, Arrieta MC, Uhrig M, Scholz R, Partida O, Borchers CH, Sansonetti PJ, Finlay BB. Diet and specific microbial exposure trigger features of environmental enteropathy in a novel murine model. Nat Commun. 2015 Aug 4;6:7806. doi: 10.1038/ncomms8806. PMID: 26241678; PMCID: PMC4532793.
Mohammed Y, Borchers CH. An extensive library of surrogate peptides for all human proteins. J Proteomics. 2015 Nov 3;129:93-97. doi: 10.1016/j.jprot.2015.07.025. Epub 2015 Jul 29. PMID: 26232110.
Petrotchenko EV, Borchers CH. HDX match software for the data analysis of top-down ECD-FTMS hydrogen/deuterium exchange experiments. J Am Soc Mass Spectrom. 2015 Nov;26(11):1895-8. doi: 10.1007/s13361-015-1213-z. Epub 2015 Jul 11. PMID: 26162650.
Horvatovich P, Lundberg EK, Chen YJ, Sung TY, He F, Nice EC, Goode RJ, Yu S, Ranganathan S, Baker MS, Domont GB, Velasquez E, Li D, Liu S, Wang Q, He QY, Menon R, Guan Y, Corrales FJ, Segura V, Casal JI, Pascual-Montano A, Albar JP, Fuentes M, Gonzalez-Gonzalez M, Diez P, Ibarrola N, Degano RM, Mohammed Y, Borchers CH, Urbani A, Soggiu A, Yamamoto T, Salekdeh GH, Archakov A, Ponomarenko E, Lisitsa A, Lichti CF, Mostovenko E, Kroes RA, Rezeli M, Végvári Á, Fehniger TE, Bischoff R, Vizcaíno JA, Deutsch EW, Lane L, Nilsson CL, Marko-Varga G, Omenn GS, Jeong SK, Lim JS, Paik YK, Hancock WS. Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project. J Proteome Res. 2015 Sep 4;14(9):3415-31. doi: 10.1021/pr5013009. Epub 2015 Jul 23. PMID: 26076068.
Pan J, Zhang S, Chou A, Hardie DB, Borchers CH. Fast Comparative Structural Characterization of Intact Therapeutic Antibodies Using Hydrogen-Deuterium Exchange and Electron Transfer Dissociation. Anal Chem. 2015 Jun 16;87(12):5884-90. doi: 10.1021/ac504809r. Epub 2015 May 26. PMID: 25927482.
Percy AJ, Yang J, Hardie DB, Chambers AG, Tamura-Wells J, Borchers CH. Precise quantitation of 136 urinary proteins by LC/MRM-MS using stable isotope labeled peptides as internal standards for biomarker discovery and/or verification studies. Methods. 2015 Jun 15;81:24-33. doi: 10.1016/j.ymeth.2015.04.001. Epub 2015 Apr 6. PMID: 25858257.
Jamnik J, García-Bailo B, Borchers CH, El-Sohemy A. Gluten Intake Is Positively Associated with Plasma α2-Macroglobulin in Young Adults. J Nutr. 2015 Jun;145(6):1256-62. doi: 10.3945/jn.115.212829. Epub 2015 Apr 8. PMID: 25855121.
Bracht T, Schweinsberg V, Trippler M, Kohl M, Ahrens M, Padden J, Naboulsi W, Barkovits K, Megger DA, Eisenacher M, Borchers CH, Schlaak JF, Hoffmann AC, Weber F, Baba HA, Meyer HE, Sitek B. Analysis of disease-associated protein expression using quantitative proteomics—fibulin-5 is expressed in association with hepatic fibrosis. J Proteome Res. 2015 May 1;14(5):2278-86. doi: 10.1021/acs.jproteome.5b00053. Epub 2015 Apr 6. PMID: 25807371.
Tremlett H, Dai DL, Hollander Z, Kapanen A, Aziz T, Wilson-McManus JE, Tebbutt SJ, Borchers CH, Oger J, Cohen Freue GV. Serum proteomics in multiple sclerosis disease progression. J Proteomics. 2015 Apr 6;118:2-11. doi: 10.1016/j.jprot.2015.02.018. Epub 2015 Mar 6. PMID: 25753122.
Makepeace KA, Serpa JJ, Petrotchenko EV, Borchers CH. Comprehensive identification of disulfide bonds using non-specific proteinase K digestion and CID-cleavable crosslinking analysis methodology for Orbitrap LC/ESI-MS/MS data. Methods. 2015 Nov 1;89:74-8. doi: 10.1016/j.ymeth.2015.02.021. Epub 2015 Mar 6. PMID: 25752848.
Abbatiello SE, Schilling B, Mani DR, Zimmerman LJ, Hall SC, MacLean B, Albertolle M, Allen S, Burgess M, Cusack MP, Gosh M, Hedrick V, Held JM, Inerowicz HD, Jackson A, Keshishian H, Kinsinger CR, Lyssand J, Makowski L, Mesri M, Rodriguez H, Rudnick P, Sadowski P, Sedransk N, Shaddox K, Skates SJ, Kuhn E, Smith D, Whiteaker JR, Whitwell C, Zhang S, Borchers CH, Fisher SJ, Gibson BW, Liebler DC, MacCoss MJ, Neubert TA, Paulovich AG, Regnier FE, Tempst P, Carr SA. Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma. Mol Cell Proteomics. 2015 Sep;14(9):2357-74. doi: 10.1074/mcp.M114.047050. Epub 2015 Feb 18. PMID: 25693799; PMCID: PMC4563721.
Solomonson M, Setiaputra D, Makepeace KAT, Lameignere E, Petrotchenko EV, Conrady DG, Bergeron JR, Vuckovic M, DiMaio F, Borchers CH, Yip CK, Strynadka NCJ. Structure of EspB from the ESX-1 type VII secretion system and insights into its export mechanism. Structure. 2015 Mar 3;23(3):571-583. doi: 10.1016/j.str.2015.01.002. Epub 2015 Feb 12. PMID: 25684576.
Geisler C, Gaisa NT, Pfister D, Fuessel S, Kristiansen G, Braunschweig T, Gostek S, Beine B, Diehl HC, Jackson AM, Borchers CH, Heidenreich A, Meyer HE, Knüchel R, Henkel C. Identification and validation of potential new biomarkers for prostate cancer diagnosis and prognosis using 2D-DIGE and MS. Biomed Res Int. 2015;2015:454256. doi: 10.1155/2015/454256. Epub 2015 Jan 15. PMID: 25667921; PMCID: PMC4312578.
Wang X, Han J, Yang J, Pan J, Borchers CH. Matrix coating assisted by an electric field (MCAEF) for enhanced tissue imaging by MALDI-MS. Chem Sci. 2015 Jan 1;6(1):729-738. doi: 10.1039/c4sc01850h. Epub 2014 Sep 16. PMID: 28706636; PMCID: PMC5494562.
Mohammed Y, Percy AJ, Chambers AG, Borchers CH. Qualis-SIS: automated standard curve generation and quality assessment for multiplexed targeted quantitative proteomic experiments with labeled standards. J Proteome Res. 2015 Feb 6;14(2):1137-46. doi: 10.1021/pr5010955. Epub 2015 Jan 16. PMID: 25546269.
Han J, Liu Y, Wang R, Yang J, Ling V, Borchers CH. Metabolic profiling of bile acids in human and mouse blood by LC-MS/MS in combination with phospholipid-depletion solid-phase extraction. Anal Chem. 2015 Jan 20;87(2):1127-36. doi: 10.1021/ac503816u. Epub 2014 Dec 24. PMID: 25496250.
Han J, Lin K, Sequeira C, Borchers CH. An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography-tandem mass spectrometry. Anal Chim Acta. 2015 Jan 7;854:86-94. doi: 10.1016/j.aca.2014.11.015. Epub 2014 Nov 15. PMID: 25479871.
Popp R, Malmström D, Chambers AG, Lin D, Camenzind AG, van der Gugten JG, Holmes DT, Pugia M, Jaremek M, Cornett S, Suckau D, Borchers CH. An automated assay for the clinical measurement of plasma renin activity by immuno-MALDI (iMALDI). Biochim Biophys Acta. 2015 Jun;1854(6):547-58. doi: 10.1016/j.bbapap.2014.10.008. Epub 2014 Oct 16. PMID: 25461795.
Brodie NI, Makepeace KA, Petrotchenko EV, Borchers CH. Isotopically-coded short-range hetero-bifunctional photo-reactive crosslinkers for studying protein structure. J Proteomics. 2015 Apr 6;118:12-20. doi: 10.1016/j.jprot.2014.08.012. Epub 2014 Sep 2. PMID: 25192908.
2014
Yassine HN, Jackson AM, Reaven PD, Nedelkov D, Nelson RW, Lau SS, Borchers CH. The Application of Multiple Reaction Monitoring to Assess Apo A-I Methionine Oxidations in Diabetes and Cardiovascular Disease. Transl Proteom. 2014 Dec 1;4-5:18-24. doi: 10.1016/j.trprot.2014.10.001. PMID: 25705587; PMCID: PMC4331021.
Petrotchenko EV, Makepeace KAT, Borchers CH. DXMSMS Match Program for Automated Analysis of LC-MS/MS Data Obtained Using Isotopically Coded CID-Cleavable Cross-Linking Reagents. Curr Protoc Bioinformatics. 2014 Dec 12;48:8.18.1-8.18.19. doi: 10.1002/0471250953.bi0818s48. PMID: 25501944.
Yi Y, Gibson J, Birks J, Han J, Borchers CH. Comment on "Profiling oil sands mixtures from industrial developments and natural groundwaters for source identification". Environ Sci Technol. 2014 Sep 16;48(18):11013-4. doi: 10.1021/es503498p. Epub 2014 Sep 3. PMID: 25184536.
Pan J, Zhang S, Parker CE, Borchers CH. Subzero temperature chromatography and top-down mass spectrometry for protein higher-order structure characterization: method validation and application to therapeutic antibodies. J Am Chem Soc. 2014 Sep 17;136(37):13065-71. doi: 10.1021/ja507880w. Epub 2014 Sep 3. PMID: 25152011.
Petrotchenko EV, Borchers CH. Modern mass spectrometry-based structural proteomics. Adv Protein Chem Struct Biol. 2014;95:193-213. doi: 10.1016/B978-0-12-800453-1.00006-3. PMID: 24985773.
Petrotchenko EV, Serpa JJ, Makepeace KA, Brodie NI, Borchers CH. (14)N(15)N DXMSMS Match program for the automated analysis of LC/ESI-MS/MS crosslinking data from experiments using (15)N metabolically labeled proteins. J Proteomics. 2014 Sep 23;109:104-10. doi: 10.1016/j.jprot.2014.06.014. Epub 2014 Jun 25. PMID: 24972318.
Percy AJ, Yang J, Chambers AG, Simon R, Hardie DB, Borchers CH. Multiplexed MRM with Internal Standards for Cerebrospinal Fluid Candidate Protein Biomarker Quantitation. J Proteome Res. 2014 Aug 1;13(8):3733-3747. doi: 10.1021/pr500317d. Epub 2014 Jun 30. PMID: 24911472.
Petrotchenko EV, Borchers CH. Application of a fast sorting algorithm to the assignment of mass spectrometric cross-linking data. Proteomics. 2014 Sep;14(17-18):1987-9. doi: 10.1002/pmic.201300486. Epub 2014 Jul 10. PMID: 24895266.
Gudavicius G, Dilworth D, Serpa JJ, Sessler N, Petrotchenko EV, Borchers CH, Nelson CJ. The prolyl isomerase, FKBP25, interacts with RNA-engaged nucleolin and the pre-60S ribosomal subunit. RNA. 2014 Jul;20(7):1014-22. doi: 10.1261/rna.042648.113. Epub 2014 May 19. PMID: 24840943; PMCID: PMC4114681.
Petrotchenko EV, Makepeace KA, Serpa JJ, Borchers CH. Analysis of protein structure by cross-linking combined with mass spectrometry. Methods Mol Biol. 2014;1156:447-63. doi: 10.1007/978-1-4939-0685-7_30. PMID: 24792007.
Percy AJ, Simon R, Chambers AG, Borchers CH. Enhanced sensitivity and multiplexing with 2D LC/MRM-MS and labeled standards for deeper and more comprehensive protein quantitation. J Proteomics. 2014 Jun 25;106:113-24. doi: 10.1016/j.jprot.2014.04.024. Epub 2014 Apr 24. PMID: 24769237.
Mohammed Y, Domański D, Jackson AM, Smith DS, Deelder AM, Palmblad M, Borchers CH. PeptidePicker: a scientific workflow with web interface for selecting appropriate peptides for targeted proteomics experiments. J Proteomics. 2014 Jun 25;106:151-61. doi: 10.1016/j.jprot.2014.04.018. Epub 2014 Apr 22. PMID: 24769191.
Parker CE, Borchers CH. Mass spectrometry based biomarker discovery, verification, and validation--quality assurance and control of protein biomarker assays. Mol Oncol. 2014 Jun;8(4):840-58. doi: 10.1016/j.molonc.2014.03.006. Epub 2014 Mar 20. PMID: 24713096; PMCID: PMC5528535.
Dang X, Scotcher J, Wu S, Chu RK, Tolić N, Ntai I, Thomas PM, Fellers RT, Early BP, Zheng Y, Durbin KR, Leduc RD, Wolff JJ, Thompson CJ, Pan J, Han J, Shaw JB, Salisbury JP, Easterling M, Borchers CH, Brodbelt JS, Agar JN, Paša-Tolić L, Kelleher NL, Young NL. The first pilot project of the consortium for top-down proteomics: a status report. Proteomics. 2014 May;14(10):1130-40. doi: 10.1002/pmic.201300438. Epub 2014 Apr 14. PMID: 24644084; PMCID: PMC4146406.
Pan J, Borchers CH. Top-down mass spectrometry and hydrogen/deuterium exchange for comprehensive structural characterization of interferons: implications for biosimilars. Proteomics. 2014 May;14(10):1249-58. doi: 10.1002/pmic.201300341. Epub 2014 Apr 10. PMID: 24574185.
Mattos KA, Oliveira VC, Berrêdo-Pinho M, Amaral JJ, Antunes LC, Melo RC, Acosta CC, Moura DF, Olmo R, Han J, Rosa PS, Almeida PE, Finlay BB, Borchers CH, Sarno EN, Bozza PT, Atella GC, Pessolani MC. Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment. Cell Microbiol. 2014 Jun;16(6):797-815. doi: 10.1111/cmi.12279. Epub 2014 Mar 21. PMID: 24552180; PMCID: PMC4262048.
Quan S, Wang L, Petrotchenko EV, Makepeace KA, Horowitz S, Yang J, Zhang Y, Borchers CH, Bardwell JC. Super Spy variants implicate flexibility in chaperone action. Elife. 2014;3:e01584. doi: 10.7554/eLife.01584. Epub 2014 Feb 4. PMID: 24497545; PMCID: PMC3910116.
Ichu TA, Han J, Borchers CH, Lesperance M, Helbing CC. Metabolomic insights into system-wide coordination of vertebrate metamorphosis. BMC Dev Biol. 2014 Feb 5;14:5. doi: 10.1186/1471-213X-14-5. PMID: 24495308; PMCID: PMC3928663.
Chambers AG, Percy AJ, Simon R, Borchers CH. MRM for the verification of cancer biomarker proteins: recent applications to human plasma and serum. Expert Rev Proteomics. 2014 Apr;11(2):137-48. doi: 10.1586/14789450.2014.877346. Epub 2014 Jan 29. PMID: 24476379.
Yassine HN, Jackson AM, Borges CR, Billheimer D, Koh H, Smith D, Reaven P, Lau SS, Borchers CH. The application of multiple reaction monitoring and multi-analyte profiling to HDL proteins. Lipids Health Dis. 2014 Jan 8;13:8. doi: 10.1186/1476-511X-13-8. PMID: 24397693; PMCID: PMC3900256.
Petrotchenko EV, Serpa JJ, Cabecinha AN, Lesperance M, Borchers CH. "Out-gel" tryptic digestion procedure for chemical cross-linking studies with mass spectrometric detection. J Proteome Res. 2014 Feb 7;13(2):527-35. doi: 10.1021/pr400710q. Epub 2014 Jan 3. PMID: 24354799.
Wang X, Han J, Pan J, Borchers CH. Comprehensive imaging of porcine adrenal gland lipids by MALDI-FTMS using quercetin as a matrix. Anal Chem. 2014 Jan 7;86(1):638-46. doi: 10.1021/ac404044k. Epub 2013 Dec 24. PMID: 24341451.
Serpa JJ, Makepeace KA, Borchers TH, Wishart DS, Petrotchenko EV, Borchers CH. Using isotopically-coded hydrogen peroxide as a surface modification reagent for the structural characterization of prion protein aggregates. J Proteomics. 2014 Apr 4;100:160-6. doi: 10.1016/j.jprot.2013.11.020. Epub 2013 Dec 3. PMID: 24316355.
Houston S, Russell S, Hof R, Roberts AK, Cullen P, Irvine K, Smith DS, Borchers CH, Tonkin ML, Boulanger MJ, Cameron CE. The multifunctional role of the pallilysin-associated Treponema pallidum protein, Tp0750, in promoting fibrinolysis and extracellular matrix component degradation. Mol Microbiol. 2014 Feb;91(3):618-34. doi: 10.1111/mmi.12482. Epub 2014 Jan 7. PMID: 24303899; PMCID: PMC3954913.
Percy AJ, Chambers AG, Yang J, Hardie DB, Borchers CH. Advances in multiplexed MRM-based protein biomarker quantitation toward clinical utility. Biochim Biophys Acta. 2014 May;1844(5):917-26. doi: 10.1016/j.bbapap.2013.06.008. Epub 2013 Jun 25. PMID: 23806606.
Parker CE, Domanski D, Percy AJ, Chambers AG, Camenzind AG, Smith DS, Borchers CH. Mass spectrometry in high-throughput clinical biomarker assays: multiple reaction monitoring. Top Curr Chem. 2014;336:117-37. doi: 10.1007/128_2012_353. PMID: 22886709.